Chemical Properties and Facts of Campathecin

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As a society publisher, everything we do is to support the scientific community – so you can trust us to always act in your best interests, and get your work the international recognition that it deserves. , Product Details of 7689-03-4, 7689-03-4, Name is Campathecin, molecular formula is C20H16N2O4, belongs to thiazines compound. In a document, author is Haggam, Reda A., introduce the new discover.

An Efficient Route for Synthesis of a New Class of Quinazolines: Synthesis of Thiazino-, Thiadiazolo-, and Thiazolo- Quinazoline Derivatives

The addition of amino group of anthranilic acid to isothiocyanate 2 provided cinnamoyl thiourea derivative 3. The compound 3 underwent different types of cyclization depending on conditions. The quinazolinthione of type 5 was obtained by treatment with Na2CO3. Quinazolinthione 5 underwent a series of transformation and oxidation reactions to form a new class of quinazoline and thiazoloquinazoline derivatives. All the compounds were tested against antimicrobial and antitumor activity.

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Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem