Tag: M.W=200-250

An article Oxygenated theranostic nanoplatforms with intracellular agglomeration behavior for improving the treatment efficacy of hypoxic tumors WOS:000459363800012 published article about ALBUMIN-MNO2 NANOPARTICLES; FE3O4 NANOPARTICLES; HIGHLY EFFICIENT; IN-SITU; DELIVERY; CELL; THERAPY; RESISTANCE; ENHANCE; MICROENVIRONMENT in [Zhou, Jun; Xue, Chencheng; Li, Menghuan; Luo, Zhong] Chongqing Univ, Sch Life Sci, Chongqing 400044, Peoples R China; [Hu, Yan; Chen, Qiufang; Li, Yanan; Li, Ke; Song, Guanbin; Cai, Kaiyong] Chongqing Univ, Minist Educ, Key Lab Biorheol Sci & Technol, Chongqing 400044, Peoples R China; [Hou, Yanhua] Chongqing Med & Pharmaceut Coll, Chongqing Engn Res Ctr Pharmaceut Sci, Chongqing 401331, Peoples R China in 2019.0, Cited 62.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride

Hypoxia plays vital roles in the development of tumor resistance against typical anticancer therapies and local reoxygenation has proved effective to overcome the hypoxia-induced chemoresistance. Perfluorocarbon (PFC) is an FDA approved oxygen carrier and currently vigorously investigated for oxygen delivery to tumors. This study reports a perfluorocarbon and etoposide (EP) loaded porous hollow Fe3O4-based theranostic nanoplatform capable of delivering oxygen to solid tumors to enhance their susceptibility against EP. Results show that oxygen could be released at a moderate rate from the porous hollow magnetic Fe3O4 nanoparticles (PHMNPs) over an extended period of time, therefore effectively reducing the hypoxia-induced EP resistance of tumor cells. Moreover, the surface of PHMNPs was modified with lactobionic acid (LA)-containing amphiphilic polymers via hydrophobic interaction, which could provide targeting effect against certain types of tumors. The hydrophilic moiety would be subsequently shed by the intratumoral GSH after cellular internalization and result in the agglomeration of nanocarriers inside tumor cells, consequently impeding the nanoparticle exocytosis to enhance their intracellular retention. The enhanced retention could elevate the intracellular EP level and effectively boost the tumor cell killing effect. In addition to the therapeutic benefits, the Fe3O4 nanocage could also be used for the magnetic resonance imaging of the tumor area. The assorted benefits of the composite nanosystem are anticipated to be advantageous for the treatment of drug-resistant hypoxic tumors.

Welcome to talk about 56-17-7, If you have any questions, you can contact Zhou, J; Xue, CC; Hou, YH; Li, MH; Hu, Y; Chen, QF; Li, YA; Li, K; Song, GB; Cai, KY; Luo, Z or send Email.. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Zou, H; Wu, QL; Li, QW; Wang, CY; Zhou, L; Hou, XH; Yuan, WZ in [Zou, Hui; Wu, Qiliang; Li, Qianwei; Zhou, Li; Hou, Xiao-Hua] Hefei Univ Technol, Sch Chem & Chem Engn, Dept Polymer Sci & Engn, Hefei 230009, Anhui, Peoples R China; [Zou, Hui; Wu, Qiliang; Li, Qianwei; Zhou, Li; Hou, Xiao-Hua] Hefei Univ Technol, Anhui Key Lab Adv Catalyt Mat & React Engn, Hefei 230009, Anhui, Peoples R China; [Wang, Chunyao; Yuan, Weizhong] Tongji Univ, Sch Mat Sci & Engn, Shanghai 201804, Peoples R China published Thermo- and redox-responsive dumbbell-shaped copolymers: from structure design to the LCST-UCST transition in 2020.0, Cited 64.0. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

A dumbbell-shaped copolymer (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) with a lower critical solution temperature (LCST) and redox responses was first synthesized by the combination of ring opening polymerization (ROP), click chemistry and atom transfer radical polymerization (ATRP). Then a dumbbell-shaped copolymer (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) with an upper critical solution temperature (UCST) and redox responses was obtained through the quaternization reaction between DMAEMA and excess 1,3-propane sultone. Both (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) were amphiphilic, and they could self-assemble into spherical micelles under certain conditions. Benefitting from the LCST-type thermoresponse of PDMAEMA and UCST-type thermoresponse of PDMAPS, both dumbbell-shaped copolymers (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) presented temperature-responsive properties. The morphology and size of their assemblies would be changed when the temperature is altered. Meanwhile, due to the redox-response of disulfide bonds, both (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) showed redox-responsive properties. When dl-dithiothreitol (DTT) was added into the systems, disulfide bonds were broken, causing the change of (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) to PCL-(PDMAEMA)(4), while (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) changed into PCL-(PDMAPS)(4). The distributions of R-h for both (PDMAEMA)(4)-PCL-SS-PCL-(PDMAEMA)(4) and (PDMAPS)(4)-PCL-SS-PCL-(PDMAPS)(4) assemblies broadened with asymmetric peaks, giving rise to curves with double peaks. After 24 h, DLS curves became symmetric with a single peak, and the R-h was about half that of the original assemblies. In the meantime, dispersed spherical micelles could be observed by TEM.

Welcome to talk about 56-17-7, If you have any questions, you can contact Zou, H; Wu, QL; Li, QW; Wang, CY; Zhou, L; Hou, XH; Yuan, WZ or send Email.. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

In 2020.0 BIOCONJUGATE CHEM published article about ALGINATE NANOGELS; DRUG-DELIVERY; TUMOR; SIZE; GLUTATHIONE; T-1; ACCUMULATION; PENETRATION; ASSEMBLIES; MICELLES in [Ma, Dan; Zhang, Jiulong; Peng, Chen; Shi, Xiangyang] Tongji Univ, Sch Med, Shanghai Peoples Hosp 10, Canc Ctr, Shanghai 200072, Peoples R China; [Ma, Dan; Shi, Menghan; Li, Xin; Fan, Yu; Jiang, Tingting; Shi, Xiangyang] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China; [Sun, Kai] Univ Michigan, Dept Mat Sci & Engn, Ann Arbor, MI 48109 USA; [Peng, Chen] Ninghai First Hosp, Ningbo 315600, Peoples R China in 2020.0, Cited 44.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride

Development of novel activable dual-mode T-1/T-2-weighted magnetic resonance (MR) contrast agents with the same composition for dynamic precision imaging of tumors has been a challenging task. Here, we demonstrated a strategy to prepare clustered Fe3O4 nanoparticles (NPs) with redox-responsiveness to tumor microenvironment to achieve switchable T-2/T-1-weighted dual-mode MR imaging applications. In this study, we first synthesized ultrasmall Fe3O4 NPs with an average size of 3.3 nm and an r, relaxivity of 4.3 mM(-1) s(-1), and then cross-linked the single Fe3O4 NPs using cystamine dihydrochloride (Cys) to form clustered Fe3O4/Cys NPs. The Fe3O4 nanoclusters (NCs) possess desirable colloidal stability, cytocompatibility, high r(2) relaxivity (26.4 mM(-1) s(-1)), and improved cellular uptake efficiency. Importantly, with the redox-responsiveness of the disulfide bond of Cys, the Fe3O4 NCs can be dissociated to form single particles under a reducing condition, hence displaying a switchable T-2/T-1-weighted MR imaging property that can be utilized for dynamic precision imaging of cancer cells in vitro and a subcutaneous tumor model in vivo due to the reductive intracellular environment of cancer cells and the tumor microenvironment. With the tumor reductive microenvironment-mediated switching of T-2 to T-1 MR effect and the ultrasmall size of the single particles that can pass through the kidney filter, the developed Fe3O4 NCs may be used as a promising switchable T-2/T-1 dual-mode MR contrast agent for precision imaging of different biosystems.

Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Atrial Arrhythmias in Clinically Manifest Cardiac Sarcoidosis: Incidence, Burden, Predictors, and Outcomes WOS:000566953100021 published article about FIBRILLATION; PREVALENCE in [Weng, Willy; Wiefels, Christiane; Nery, Pablo B.; Celiker-Guler, Emel; Promislow, Steven; Medor, Maria C.; Spence, Stewart; Odabashian, Roupen; Alqarawi, Wael; Juneau, Daniel; de Kemp, Rob; Leung, Eugene; Beanlands, Rob; Birnie, David] Univ Ottawa, Heart Inst, Div Cardiol, 40 Ruskin St, Ottawa, ON K1Y 4W7, Canada; [Chakrabarti, Santabhanu] Univ British Columbia, Div Cardiol, Vancouver, BC, Canada; [Healey, Jeff S.] McMaster Univ, Populat Hlth Res Inst, Hamilton, ON, Canada; [Hruczkowski, Tomasz W.] Univ Alberta, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; [Quinn, F. Russell] Libin Cardiovasc Inst Alberta, Calgary, AB, Canada; [Juneau, Daniel] Univ Montreal, Ctr Hosp, Dept Nucl Med & Radiol, Montreal, PQ, Canada in 2020.0, Cited 19.0. Name: 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Background: Recent data have suggested a substantial incidence of atrial arrhythmias (AAs) in cardiac sarcoidosis (CS). Our study aims were to first assess how often AAs are the presenting feature of previously undiagnosed CS. Second, we used prospective follow-up data from implanted devices to investigate AA incidence, burden, predictors, and response to immunosuppression. Methods and Results: This project is a substudy of the CHASM-CS (Cardiac Sarcoidosis Multicenter Prospective Cohort Study; NCT01477359). Inclusion criteria were presentation with clinically manifest cardiac sarcoidosis, treatment-naive status, and implanted with a device that reported accurate AA burden. Data were collected at each device interrogation visit for all patients and all potential episodes of AA were adjudicated. For each intervisit period, the total AA burden was obtained. A total of 33 patients met the inclusion criteria (aged 56.1 +/- 7.7 years, 45.5% women). Only 1 patient had important AAs as a part of the initial CS presentation. During a median follow-up of 49.1 months, 11 of 33 patients (33.3%) had device-detected AAs, and only 2 (6.1%) had a clinically significant AA burden. Both patients had reduced burden after CS was successfully treated and there was no residual fluorodeoxyglucose uptake on positron emission tomography scan. Conclusions: First, we found that AAs are a rare presenting feature of clinically manifest cardiac sarcoidosis. Second, AAs occurred in a minority of patients at follow-up; the burden was very low in most patients. Only 2 patients had clinically significant AA burden, and both had a reduction after CS was treated. REGISTRATION: URL: https://www.clinicaltrials.gov; unique identifier NCT01477359.

Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.. Name: 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Recently I am researching about DRUG-DELIVERY; NANOPARTICLES; COMBINATION; MICELLES; CELLS, Saw an article supported by the Ministry of Science and Technology, TaiwanMinistry of Science and Technology, Taiwan [MOST 108-2923E-011-005-MY3, 108-2221-E-011-110-MY3]. Category: thiazines. Published in MDPI in BASEL ,Authors: Andrgie, AT; Birhan, YS; Mekonnen, TW; Hanurry, EY; Darge, HF; Lee, RH; Chou, HY; Tsai, HC. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

Polymeric prodrug-based delivery systems have been extensively studied to find a better solution for the limitations of a single drug and to improve the therapeutic and pharmacodynamics properties of chemotherapeutic agents, which can lead to efficient therapy. In this study, redox-responsive disulfide bond-containing amphiphilic heparin-chlorambucil conjugated polymeric prodrugs were designed and synthesized to enhance anti-tumor activities of chlorambucil. The conjugated prodrug could be self-assembled to form spherical vesicles with 61.33% chlorambucil grafting efficiency. The cell viability test results showed that the prodrug was biocompatible with normal cells (HaCaT) and that it selectively killed tumor cells (HeLa cells). The uptake of prodrugs by HeLa cells increased with time. Therefore, the designed prodrugs can be a better alternative as delivery vehicles for the chlorambucil controlled release in cancer cells.

Category: thiazines. Welcome to talk about 56-17-7, If you have any questions, you can contact Andrgie, AT; Birhan, YS; Mekonnen, TW; Hanurry, EY; Darge, HF; Lee, RH; Chou, HY; Tsai, HC or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Name: 2,2′-Disulfanediyldiethanamine dihydrochloride. Lee, JP; Hwang, H; Chae, S; Kim, JM in [Lee, Jong Pil; Hwang, Hyemin; Chae, Songa; Kim, Jong-Man] Hanyang Univ, Dept Chem Engn, Seoul 04763, South Korea; [Kim, Jong-Man] Hanyang Univ, Inst Nano Sci & Technol, Seoul 04763, South Korea published A reversibly mechanochromic conjugated polymer in 2019.0, Cited 35.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7.

A reversibly mechanochromic conjugated polymer has been developed. The polymer, polydiacetylene (PDA), obtained by thermal polymerization of a diphenyldisulfide-containing bisdiacetylene undergoes a blue-to-green color change upon grinding. The original blue color of the PDA is regenerated via a metastable red-color state by utilizing a thermochromic (heating-cooling) process.

Name: 2,2′-Disulfanediyldiethanamine dihydrochloride. Welcome to talk about 56-17-7, If you have any questions, you can contact Lee, JP; Hwang, H; Chae, S; Kim, JM or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Recommanded Product: 2,2′-Disulfanediyldiethanamine dihydrochloride. I found the field of Chemistry very interesting. Saw the article Combined pH-responsive chemotherapy and glutathione-triggered photosensitization to overcome drug-resistant hepatocellular carcinoma – a SPP/JPP Young Investigator Award paper published in 2020.0, Reprint Addresses Lo, PC (corresponding author), City Univ Hong Kong, Dept Biomed Sci, Kowloon, Tat Chee Ave, Hong Kong, Peoples R China.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride.

Doxorubicin (DOX) resistance, which results in a reduced accumulation of DOX in the nucleus and hence decreased DNA damage, is a major challenge for chemotherapy against hepatocellular carcinoma. In this paper, we combined chemotherapy with photodynamic therapy (PDT) to combat DOX-resistant human hepatocellular carcinoma cells. We have prepared the polymeric micelles conjugating with DOX and zinc(II) phthalocyanine (ZnPc) through a pH-responsive hydrazone linker and a glutathione (GSH)-responsive disulfide linker, respectively. The polymeric micelles (DOX-ZnPc-micelles) exhibited a spherical shape with a size of about 98 mn diameter and showed excellent stability in aqueous solution. Due to the self-quenching of the ZnPc inside the micelles, DOX-ZnPc-micelles did not emit fluorescence upon red light irradiation. Drug release experiments verified that DOX and ZnPc could be released under acidic conditions and reducing environments, respectively. A higher concentration of DOX was internalized into DOX-resistant R-HepG2 cells through the delivery of polymeric micelles when compared with the free DOX, hence DOX-ZnPc-micelles exhibited a significant enhancement in anticancer activity. The IC50 value of DOX against R-HepG2 cells was found to be 21 mu M when combined with PDT and it was 5-fold less than that of a single treatment of DOX (102 mu M). The DOX-ZnPc-micelles could induce cell apoptosis and necrosis on R-HepG2 cells by combined therapeutic modalities, while these micelles induced only apoptosis on IiepG2 cells. We have demonstrated that utilization of polymeric micelles can significantly enhance the cellular uptake and cytotoxicity of DOX against R-HepG2 cells when compared with free DOX. Moreover, PDT can act as an adjuvant therapeutic modality and combine with chemotherapy to further improve therapeutic efficacy. Overall speaking, DOX-ZnPc-micelles can overcome DOX resistance and induce a synergistic therapeutic effect against DOX-resistant R-HepG2 cells, hence improving the therapeutic efficacy when compared with monotherapy.

Recommanded Product: 2,2′-Disulfanediyldiethanamine dihydrochloride. Welcome to talk about 56-17-7, If you have any questions, you can contact Gao, D; Lo, PC or send Email.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Recently I am researching about PEPTIDE; NANOPARTICLES; HYDROGELS; PROTEINS; MATTER, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [81722026, 31900998, 81971731]; CAMS Innovation Fund for Medical Sciences (CIFMS) [2016-I2M-3-022]; Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences [2018PT35031]; Science Foundation for Distinguished Young Scholars of Tianjin [18JCJQJC47300]; Drug Innovation Major Project [2018ZX09711-001]. Recommanded Product: 56-17-7. Published in FRONTIERS MEDIA SA in LAUSANNE ,Authors: Wang, ZY; Ren, CH; Shang, YN; Yang, CH; Guo, QX; Chu, LP; Liu, JF. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

The utilization of nanotechnology to deliver vaccines and modulate immunity has shown great potential in cancer therapy. Peptide-based supramolecular hydrogels as novel vaccine adjuvants have been found to effectively improve the immune response and tumor curative effect. In this study, we designed a set of reduction-responsive self-assembled peptide precursors (Fbp-G(D)F(D)F(D)Y(D)(E, S, or K)-ss-ERGD), which can be reduced by glutathione (GSH) into Fbp-G(D)F(D)F(D)Y(D)(E, S or K)-SH for forming of hydrogel with different surface properties (E-gel, S-gel, and K-gel, respectively). Using the same method, co-assembled hydrogel vaccines (E-vac, S-vac, and K-vac, respectively) can also be prepared by mixing different precursors with antigens before GSH reduction. Through TEM observation of the nanostructure, we found that all the co-assembled hydrogels, especially K-vac, possessed much denser and more unified nanofiber networks as compared with antigen-free hydrogels, which were very suitable for antigen storage and vaccine delivery. Although the three peptides adopted similar beta-sheet secondary structures, the mechanical properties of their resulted co-assembled hydrogel vaccines were obviously different. Compared to E-vac, S-vac had a much weaker mechanical property, while K-vac had a much higher.In vivoexperiments, co-assembled hydrogel vaccines, especially K-vac, also promoted antibody production and anti-tumor immune responses more significantly than the other two vaccines. Our results demonstrated that co-assembled hydrogels formed by peptides and antigens co-assembly could act as effective vaccine delivery systems for boosting antibody production, and different immune effects can be acquired by tuning the surface properties of the involved self-assembling peptides.

Welcome to talk about 56-17-7, If you have any questions, you can contact Wang, ZY; Ren, CH; Shang, YN; Yang, CH; Guo, QX; Chu, LP; Liu, JF or send Email.. Recommanded Product: 56-17-7

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

COA of Formula: C4H14Cl2N2S2. Authors Zhou, J; Wu, RN; Chen, YR; Tan, YB in ELSEVIER published article about in [Zhou, Jing; Wu, Ruonan; Chen, Yanru; Tan, Yebang] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China; [Tan, Yebang] Shandong Univ, Key Lab Special Funct Aggregated Mat, Minist Educ, Jinan 250100, Peoples R China in 2021.0, Cited 42.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

A triply responsive amphiphilic polymer containing poly (ethylene glycol) (PEG) and pyrene linked by a disulfide bond (PEO-SS-PY) was synthesized. Benefiting from its amphiphilicity, PEO-SS-PY could self-assemble into 126 nm micelles in water. PEO-SS-PY with CB[7] forms a 1:1 pseudorotaxane polymer (PEO-SS-Py@CB[7]) in aqueous solution. After the formation of host-guest complex, the micelles size increased to 136 nm and the fluorescence emission intensity increased. Glutathione would break the disulfide bond, leading to the dissociation of the micelles. Spermine and adamantanamine hydrochloride would dissociate the host-guest complex, leading to change of micelle size and decrease of fluorescence intensity. More interestingly, this self-assembly micelle displayed highly sensitive response to Fe3+. Because the effective absorption of Fe3+ hindered the absorption of PEO-SS-Py@CB[7] at the excitation wavelength of 405 nm, Fe3+ distinctly quenched the fluorescence emission of PEO-SS-Py@CB[7], whereas, a very low changes of intensity was observed for other metal ions. Results of this paper provide a new idea for the combination of metal ion detection and controlled release.

Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.. COA of Formula: C4H14Cl2N2S2

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Preparation of redox responsive modified xanthan gum nanoparticles and the drug controlled release WOS:000538407700001 published article about ZWITTERIONIC NANOPARTICLES; POLYMERIC MICELLES; PH; DELIVERY; ACID); NANOGELS; POLY(ETHYLENE; COPOLYMER in [Feng, Zhiyun] Yangtze Univ, Coll Chem & Environm Engn, Jingzhou, Peoples R China; [Xu, Jie; Ni, Caihua] Jiangnan Univ, Sch Chem & Mat Engn, Wuxi, Jiangsu, Peoples R China in 2021.0, Cited 35.0. COA of Formula: C4H14Cl2N2S2. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

A new kind of redox responsive nanoparticles was prepared through the modification and crosslinking reaction of xanthan gum. The nanoparticles had regular spherical shapes with diameters ranging from 110 to 180 nm. The nanoparticles showed good redox responsiveness. Doxorubicin (DOX) was loaded in the nanoparticles via ionic interaction with SO3-, for increasing the drug loading rate and avoiding drug leakage. The in vitro drug release could be controlled by pH and reduction conditions simulated to the internal environment of tumor cells. The nanoparticles were biocompatible and could be potentially applied as anti-cancer drug vehicles for targeted release.

COA of Formula: C4H14Cl2N2S2. Bye, fridends, I hope you can learn more about C4H14Cl2N2S2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem