Category: 56-17-7

I found the field of Pharmacology & Pharmacy very interesting. Saw the article Investigation on vitamin e succinate based intelligent hyaluronic acid micelles for overcoming drug resistance and enhancing anticancer efficacy published in 2019.0. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride, Reprint Addresses Zhang, HJ; Zhang, ZZ (corresponding author), Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou, Henan, Peoples R China.; Zhang, HJ; Zhang, ZZ (corresponding author), Key Lab Targeting Therapy & Diag Crit Dis, Zhengzhou, Henan, Peoples R China.; Zhang, HJ; Zhang, ZZ (corresponding author), Collaborat Innovat Ctr New Drug Res & Safety Eval, Zhengzhou, Henan, Peoples R China.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

Multidrug resistance (MDR) is a major reason for anticancer chemotherapy failure, and P-glycoprotein (P-gp) over-expressing on tumor cells is considered as the important target to overcome MDR. Emerging reports have showed that vitamin E (VE) can cause significant reversal of MDR due to inhibition of ATPase activity. Accordingly, we synthesized hyaluronic acid (HA) conjugated vitamin E succinate (VES) polymer, which can self-assemble into micelles and thus achieve high drug (paclitaxel (PTX) used as model drug) encapsulation as well as tumor accumulation owing to the enhanced permeability and retention (EPR) effect and HA active targeting ability. In addition, the linker between HA and VES utilized in this work was disulfide bond with reduction-sensitive property, which would respond to high glutathione (GSH) concentration in tumor cytoplasmic environment and trigger HA-CYS-VES polymer disassociation and drug release. In vitro, PTX loaded HA-CYS-VES demonstrated enhanced cytotoxicity, high apoptosis-inducing activities and reversal effects of PTX on MCF-7/Adr cells, compared to PTX. Also, cellular uptake and intracellular PTX accumulation tests displayed that PTX loaded HA-CYS-VES could more efficiently enter tumor cells and selectively release drug in cytosol so as to facilitate its function on microtubule. More importantly, PTX loaded HA-CYS-VES showed better tumor targeting ability, improved antitumor efficacy and low adverse effects on tumor-bearing mice. In conclusion, PTX loaded HA-CYS-VES exhibited a great potential for reversing MDR in anticancer chemotherapeutics.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Hou, L; Tian, CY; Chen, DD; Yuan, YJ; Yan, YS; Huang, QX; Zhang, HJ; Zhang, ZZ or concate me.. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

In 2020.0 J BIOMED MATER RES B published article about MESENCHYMAL STEM-CELLS; OPTIMIZATION; CULTURE; DIFFERENTIATION; EXPANSION; SYSTEM; GROWTH; HMSCS in [Dosta, Pere; Ferber, Shiran; Zhang, Yi; Wang, Kui; Ros, Albert; Artzi, Natalie] MIT, Inst Med Engn & Sci, 77 Massachusetts Ave, Cambridge, MA 02139 USA; [Dosta, Pere; Ferber, Shiran; Zhang, Yi; Wang, Kui; Ros, Albert; Artzi, Natalie] Harvard Med Sch, Brigham & Womens Hosp, Div Engn Med, Dept Med, Boston, MA 02115 USA; [Uth, Nicholas; Levinson, Yonatan; Abraham, Eytan] Res & Technol, Walkersville, MD USA; [Artzi, Natalie] Broad Inst Harvard & MIT, Cambridge, MA USA in 2020.0, Cited 33.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7. Safety of 2,2′-Disulfanediyldiethanamine dihydrochloride

Microcarriers, including crosslinked porous gelatin beads (Cultispher G) are widely used as cell carriers for cell therapy applications. Microcarriers can support a range of adherent cell types in stirred tank bioreactor culture, which is scalable up to several thousands of liters. Cultispher G in particular is advantageous for cell therapy applications because it can be dissolved enzymatically, and thus cells can be harvested without the need to perform a large-scale cell-bead filtration step. This enzymatic dissolution, however, is challenged by the slow degradation of the carriers in the presence of enzymes as new extracellular matrix is being deposited by the proliferating cells. This extended dissolution timelimits the yield of cell recovery while compromising cellular viability. We report herein the development of crosslinked porous gelatin beads that afford rapid, stimuli-triggered dissolution for facile cell removal using human mesenchymal stem cells (hMSC) as a model system. We successfully fabricated redox-sensitive beads (RS beads) and studied their cell growth, dissolution time and cell yield, compared to regular gelatin-based beads (Reg beads). We have shown that RS beads allow for much faster dissolution compared to Reg beads, supporting better hMSC detachment and recovery following 8 days of culture in spinner flasks, or in 3L bioreactors. These newly synthesized RS beads show promise as cellular microcarriers and can be used for scale-up manufacturing of different cell types while providing on-demand degradation for facile cell retrieval.

Safety of 2,2′-Disulfanediyldiethanamine dihydrochloride. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Dosta, P; Ferber, S; Zhang, Y; Wang, K; Ros, A; Uth, N; Levinson, Y; Abraham, E; Artzi, N or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Supramolecular Emulsion Interfacial Polymerization WOS:000459948600016 published article about POLYMERS; COVALENT in [Zhang, Shuai; Qin, Bo; Huang, Zehuan; Xu, Jiang-Fei; Zhang, Xi] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China in 2019.0, Cited 52.0. Computed Properties of C4H14Cl2N2S2. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

A new method of supramolecular emulsion interfacial polymerization is developed, which can be used to fabricate supramolecular polymeric nanospheres. We designed a water-soluble monomer containing two maleimide end groups, acting as both building block and surfactant, and an oil-soluble supramonomer bearing two thiol groups connected by quadruple hydrogen bonds. With the assist of ultrasonication, hollow nanospheres can be controllably prepared by thiol-maleimide reaction of two monomers at the emulsion interface, which exhibit good stability and dynamic property. In addition, the encapsulated guest molecules could be controllably released from the supramolecular polymeric nanospheres, owing to their stimuli-responsiveness. It is anticipated that this approach will enrich the methodology of supramolecular polymerization and can be applied to constructing supramolecular materials with controllable structures and functions.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Zhang, S; Qin, B; Huang, ZH; Xu, JF; Zhang, X or concate me.. Computed Properties of C4H14Cl2N2S2

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Authors Pinter, ZW; Farnell, CG; Huntley, S; Patel, HA; Peng, JG; McMurtrie, J; Ray, JL; Naranje, S; Shah, AB in SPRINGER HEIDELBERG published article about STRESS-FRACTURES; INJURIES in [Pinter, Zachariah W.; Farnell, Chason G.; Huntley, Samuel; Patel, Harshadkumar A.; Peng, Jianguang; McMurtrie, James; Ray, Jessyca L.; Naranje, Sameer; Shah, Ashish B.] Univ Alabama Birmingham, Dept Orthopaed Surg, 1313 13th St South, Birmingham, AL 35205 USA in 2020.0, Cited 20.0. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Background Turf toe injuries, though most common in athletes, can also occur in non-athletes. No study exists in the current literature investigating operative outcomes in non-athlete patients with chronic turf toe injury. In this study, we present our outcomes on operatively treated turf toe injuries in non-athletes in the only cohort yet studied. Methods Using ICD-10 codes, we assembled a cohort of 12 patients who underwent operative repair of chronic turf toe injury from January 2012 through January 2018 at the investigating institution. These 12 patients were evaluated to determine demographic information, method of injury, length of time from injury to surgery, clinical and radiologic characteristics of the injury, and operative outcomes including mean preoperative and postoperative VAS (Visual Analog Scale) scores, preoperative and postoperative FFI (Foot Function Index) scores, and postoperative complications. Results On initial clinical presentation, all 12 patients had local tenderness with associated painful range of motion. Four patients had restricted range of motion, all patients had a positive Lachman test, two had local edema, and eight had hallux valgus deformity. Mean VAS improved from 4.6 (range 2-9) to 1 (range 0-4). Mean FFI improved from 102.5 (range 56-177) to 61.75 (range 23-144). All patients had a negative Lachman test at final follow-up. No patients developed major complications or required revision surgery. Conclusions Our study is the first to investigate operative outcomes following chronic turf toe injury in non-athlete patients. Based on our study, surgeons and patients can expect significant improvement in overall pain and function following surgery.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Pinter, ZW; Farnell, CG; Huntley, S; Patel, HA; Peng, JG; McMurtrie, J; Ray, JL; Naranje, S; Shah, AB or concate me.. Quality Control of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

I found the field of Chemistry; Materials Science very interesting. Saw the article A glutathione-activated carrier-free nanodrug of triptolide as a trackable drug delivery system for monitoring and improving tumor therapy published in 2021.0. Name: 2,2′-Disulfanediyldiethanamine dihydrochloride, Reprint Addresses Zeng, RS (corresponding author), Guilin Univ Elect Technol, Sch Mat Sci & Engn, Sch Life & Environm Sci, Guilin 541004, Peoples R China.; Zhang, PF; Gong, P (corresponding author), Chinese Acad Sci, Guangdong Key Lab Nanomed,Shenzhen Inst Adv Techn, Shenzhen Engn Lab Nanomed & Nanoformulat,Inst Bio, CAS Key Lab Hlth Informat,CAS HK Joint Lab Biomat, Shenzhen 518055, Peoples R China.; Zeng, RS (corresponding author), Guangxi Univ, Sch Phys Sci & Technol, Nanning 530004, Peoples R China.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

Triptolide (TP) is one of the most common systemic treatments for inflammatory and immune diseases in China for centuries. However, TP exhibits some disadvantages, such as poor solubility in water, poor bioavailability, liver toxicity, renal toxicity, and other side effects. In order to reduce the adverse effects of TP, researchers have developed numerous strategies to address the adverse properties of triptolide. Nano-carrier-based triptolide delivery systems represent an emerging technology and are one of the strategies of nanomedicine that combines diagnostic and therapeutic applications in a single agent. In this approach, we developed a glutathione-activated carrier-free nanodrug of triptolide (CyssTPN) as a trackable drug delivery system. In this system, CyssTP self-assemble to form a carrier-free nanodrug, which possesses a monodisperse spherical morphology with hydrodynamic average sizes of about 50 nm. In addition, CyssTPN had good stability under different physiological conditions (pH, high salt, etc.). Apart from cellular imaging and cell uptake, CyssTPN can be tracked by the activation of TP ability in real-time and applied for cancer cell treatment efficiently. The result showed that CyssTPN could improve solubility, reduce the side effects, and increase the bioavailability of triptolide. It could also track triptolide activation timely and tumor therapy successfully.

Name: 2,2′-Disulfanediyldiethanamine dihydrochloride. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Li, Y; Zhou, LH; Zhu, BD; Xiang, JJ; Du, J; He, MW; Fan, XX; Zhang, PF; Zeng, RS; Gong, P or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Investigation of 2,2 ‘-diaminodiethyl disulfide for mild steel protection in acid solution WOS:000529345400010 published article about 1 M HCL; CORROSION INHIBITION PERFORMANCE; ECO-FRIENDLY INHIBITOR; X70 STEEL; DERIVATIVES; EXTRACT; MEDIA; EFFICIENCY; COMPOUND in [Sigircik, Gokmen] Cukurova Univ, Fac Sci & Letters, Dept Chem, TR-01330 Adana, Turkey in 2020.0, Cited 43.0. Safety of 2,2′-Disulfanediyldiethanamine dihydrochloride. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

Inhibition performance of 2,2′-diaminodiethyl disulfide (DA) was studied against mild steel (MS) corrosion in 0.5 M HCl. Electrochemical impedance spectroscopy (EIS), potentiodynamic (PD) polarization measurements were utilized to investigate the influence of inhibitor concentration and temperature on efficiency, as well as explanation of inhibition mechanism. Scanning electron microscopy (SEM) analysis was utilized to investigate the surface damages due to corrosion, in the absence and presence of inhibitor molecules. PD data revealed that the studied molecule exhibits mixed type inhibitor behavior on steel surface. Moreover, the calculated free adsorption energy (Delta G(ads)(o)) value is 38.45 kJ mol(-1), which indicates to strong adsorptive interaction by both physical and chemical means. UV-Visible study results supported the idea that there is strong interaction between the surface with the molecule, via its -S and -N atoms. As a consequence, 91.7% inhibition efficiency was determined in presence of 1.0 mM DA. (C) 2020 Elsevier B.V. All rights reserved.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Sigircik, G or concate me.. Safety of 2,2′-Disulfanediyldiethanamine dihydrochloride

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Synthesis and Guest-Binding Properties of pH/Reduction Dual-Responsive Cyclophane Dimer published in 2021.0. Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride, Reprint Addresses Hayashida, O (corresponding author), Fukuoka Univ, Dept Chem, Fac Sci, Nanakuma 8-19-1, Fukuoka 8140180, Japan.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride

A water-soluble cyclophane dimer having two disulfide groups as a reduction-responsive cleavable bond as well as several acidic and basic functional groups as a pH-responsive ionizable group 1 was successfully synthesized. It was found that 1 showed pH-dependent guest-binding behavior. That is, 1 strongly bound an anionic guest, 6-p-toluidinonaphthalene-2-sulfonate (TNS) with binding constant (K/M-1) for 1:1 host-guest complexes of 9.6 x 10(4) M-1 at pH 3.8, which was larger than those at pH 7.4 and 10.7 (6.0 x 10(4) and 2.4 x 10(4) M-1, respectively), indicating a favorable electrostatic interaction between anionic guest and net cationic 1. What is more, release of the entrapped guest molecules by 1 was easily controlled by pH stimulus. Large favorable enthalpies (Delta H) for formation of host-guest complexes were obtained under the pH conditions employed, suggesting that electrostatic interaction between anionic TNS and 1 was the most important driving force for host-guest complexation. Such contributions of Delta H for formation of host-guest complexes decreased along with increased pH values from acidic to basic solutions. Upon addition of dithiothreitol (DTT) as a reducing reagent to an aqueous PBS buffer (pH 7.4) containing 1 and TNS, the fluorescence intensity originating from the bound guest molecules decreased gradually. A treatment of 1 with DTT gave 2, having less guest-binding affinity by the cleavage of disulfide bonds of 1. Consequently, almost all entrapped guest molecules by 1 were released from the host. Moreover, such reduction-responsive cleavage of 1 and release of bound guest molecules was performed more rapidly in aqueous buffer at pH 10.7.

Application In Synthesis of 2,2′-Disulfanediyldiethanamine dihydrochloride. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Hayashida, O; Tanaka, Y; Miyazaki, T or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

In 2020.0 MOL MED REP published article about HYALURONIC-ACID; RELEASE; PERMEABILITY; LIPOSOMES in [Jiang, Jianwei; Zhong, Xiaoming] Zhejiang Chinese Med Univ, Coll Pharmaceut Sci, 548 Binwen Rd, Hangzhou 310053, Zhejiang, Peoples R China; [Jiang, Jianwei; Zhang, Hongyan; Wang, Chunlei] Zhejiang Canc Hosp, Dept Pharm, 38 Guangji Rd, Hangzhou 310022, Zhejiang, Peoples R China in 2020.0, Cited 26.0. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7. Computed Properties of C4H14Cl2N2S2

Drugs, including small molecule anticancer drugs, have to be delivered and released into the cytoplasm or nucleus in order to elicit a therapeutic effect. In the present study, a novel corona core-shell nanoparticle was proposed for enhanced cellular uptake and light-responsive intracellular release. Light-responsive core-shell nanoparticles, i.e., gold nanoparticles-coated liposomes (CS), were prepared and further modified with hyaluronic acid (HA) (CCS). HA modification enhances the endocytosis of the nanoparticles by HA receptor-expressing cells, while the plasmonic properties of gold nanoparticles enable their light-triggered drug release. The results demonstrated that the uptake of CCS in HA receptor-expressing MDA-MB-231R cells was significantly enhanced compared with unmodified CS. Nanosecond pulsed laser irradiation (700 nm; 100 mJ/cm(2); 5 pulses) rapidly triggered the intracellular release of a fluorescent dye, 6-carboxyfluorescein (6-CF), from CCS and CS trapped in endolysosomes. The released 6-CF was evenly distributed throughout the entire cytosol and nucleus. Finally, the cytotoxicity of doxorubicin towards MDA-MB-231 cells was significantly increased by CCS delivery upon pulsed laser irradiation. In conclusion, with enhanced cellular uptake and light-triggered intracellular release, CCS significantly enhanced the therapeutic effects of doxorubicin, and may serve as a promising avenue for intracellular drug delivery.

Computed Properties of C4H14Cl2N2S2. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Jiang, JW; Zhong, XM; Zhang, HY; Wang, CL or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

An article Self-assembled nanoparticles of reduction-sensitive poly (lactic-co-glycolic acid)-conjugated chondroitin sulfate A for doxorubicin delivery: preparation, characterization and evaluation WOS:000468538200014 published article about POLYMERIC MICELLES; INTRACELLULAR DELIVERY; MULTIDRUG-RESISTANCE; BLOCK-COPOLYMERS; BREAST-CANCER; DRUG; CORE; PLGA; RELEASE; NANOCARRIERS in [Wang, Xu-Feng; Ren, Jin; He, Hai-Qing; Li, Zi-Xin; Zhao, Jian-Guo; Yu, Jing-Mou] Jiujiang Univ, Sch Pharm & Life Sci, 320 Xunyang East Rd, Jiujiang 332000, Peoples R China; [Liang, Liang] Jiujiang Univ, Analyt & Testing Ctr, Jiujiang, Peoples R China; [Xie, Xin] Jiujiang Univ, Coll Basic Med Sci, Jiujiang, Peoples R China in 2019.0, Cited 47.0. Product Details of 56-17-7. The Name is 2,2′-Disulfanediyldiethanamine dihydrochloride. Through research, I have a further understanding and discovery of 56-17-7

In this study, reduction-sensitive self-assembled polymer nanoparticles based on poly (lactic-co-glycolic acid) (PLGA) and chondroitin sulfate A (CSA) were developed and characterized. PLGA was conjugated with CSA via a disulfide linkage (PLGA-ss-CSA). The critical micelle concentration (CMC) of PLGA-ss-CSA conjugate is 3.5 mu g/mL. The anticancer drug doxorubicin (DOX) was chosen as a model drug, and was effectively encapsulated into the nanoparticles (PLGA-ss-CSA/DOX) with high loading efficiency of 15.1%. The cumulative release of DOX from reduction-sensitive nanoparticles was only 34.8% over 96h in phosphate buffered saline (PBS, pH 7.4). However, in the presence of 20mM glutathione-containing PBS environment, DOX release was notably accelerated and almost complete from the reduction-sensitive nanoparticles up to 96h. Moreover, efficient intracellular DOX release of PLGA-ss-CSA/DOX nanoparticles was confirmed by CLSM assay in A549 cells. In vitro cytotoxicity study showed that the half inhibitory concentrations of PLGA-ss-CSA/DOX nanoparticles and free DOX against A549 cells were 1.141 and 1.825 mu g/mL, respectively. Therefore, PLGA-ss-CSA/DOX nanoparticles enhanced the cytotoxicity of DOX in vitro. These results suggested that PLGA-ss-CSA nanoparticles could be a promising carrier for drug delivery.

About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Wang, XF; Ren, J; He, HQ; Liang, L; Xie, X; Li, ZX; Zhao, JG; Yu, JM or concate me.. Product Details of 56-17-7

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem

Recommanded Product: 2,2′-Disulfanediyldiethanamine dihydrochloride. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Synthesis and Guest-Binding Properties of pH/Reduction Dual-Responsive Cyclophane Dimer published in 2021.0, Reprint Addresses Hayashida, O (corresponding author), Fukuoka Univ, Dept Chem, Fac Sci, Nanakuma 8-19-1, Fukuoka 8140180, Japan.. The CAS is 56-17-7. Through research, I have a further understanding and discovery of 2,2′-Disulfanediyldiethanamine dihydrochloride.

A water-soluble cyclophane dimer having two disulfide groups as a reduction-responsive cleavable bond as well as several acidic and basic functional groups as a pH-responsive ionizable group 1 was successfully synthesized. It was found that 1 showed pH-dependent guest-binding behavior. That is, 1 strongly bound an anionic guest, 6-p-toluidinonaphthalene-2-sulfonate (TNS) with binding constant (K/M-1) for 1:1 host-guest complexes of 9.6 x 10(4) M-1 at pH 3.8, which was larger than those at pH 7.4 and 10.7 (6.0 x 10(4) and 2.4 x 10(4) M-1, respectively), indicating a favorable electrostatic interaction between anionic guest and net cationic 1. What is more, release of the entrapped guest molecules by 1 was easily controlled by pH stimulus. Large favorable enthalpies (Delta H) for formation of host-guest complexes were obtained under the pH conditions employed, suggesting that electrostatic interaction between anionic TNS and 1 was the most important driving force for host-guest complexation. Such contributions of Delta H for formation of host-guest complexes decreased along with increased pH values from acidic to basic solutions. Upon addition of dithiothreitol (DTT) as a reducing reagent to an aqueous PBS buffer (pH 7.4) containing 1 and TNS, the fluorescence intensity originating from the bound guest molecules decreased gradually. A treatment of 1 with DTT gave 2, having less guest-binding affinity by the cleavage of disulfide bonds of 1. Consequently, almost all entrapped guest molecules by 1 were released from the host. Moreover, such reduction-responsive cleavage of 1 and release of bound guest molecules was performed more rapidly in aqueous buffer at pH 10.7.

Recommanded Product: 2,2′-Disulfanediyldiethanamine dihydrochloride. About 2,2′-Disulfanediyldiethanamine dihydrochloride, If you have any questions, you can contact Hayashida, O; Tanaka, Y; Miyazaki, T or concate me.

Reference:
Thiazine – an overview | ScienceDirect Topics,
,Thiazine | C4H5NS – PubChem